Snapshot A 34-year-old man presents to a local urgent care after returning from a trip to Africa. He has endured multiple mosquito bites throughout his 2-week safari trip. He states that, like several members of his tour group, he has had a 3-day history of fever, non-itchy rash, and myalgias. One tour group member, however, developed seizures and confusion. This patient is scared that he may also develop severe symptoms like seizures. On physical exam, he has conjunctival injection and a papular rash on his trunk and legs. Given his age and current symptoms, his physician reassures him that it is highly unlikely but to watch out for any signs of meningoencephalitis. Introduction Classification login to view 4 more bullets Epidemiology login to view 5 more bullets Pathogenesis login to view 4 more bullets Associated conditions login to view 2 more bullets Prognosis login to view 2 more bullets Presentation Symptoms login to view 11 more bullets Physical exam login to view 11 more bullets Imaging Magnetic resonance imaging (MRI) login to view 4 more bullets Studies Labs login to view 7 more bullets Making the diagnosis login to view 1 more bullet Differential Dengue fever login to view 2 more bullets Treatment Management approach login to view 1 more bullet Conservative login to view 7 more bullets Complications Rhabdomyolysis Guillain-Barré syndrome