Snapshot A 55-year-old man presents to the emergency department with pain in his heel. His symptoms began a few days ago, when he developed heel pain that was unresponsive to acetaminophen and was associated with fever. He also endorses generalized malaise. Medical history is remarkable for diabetes complicated by peripheral neuropathy. Physical examination is notable for an erythematous and ulcerative lesion of the heal. A probe-to-bone test is positive. A bone biopsy is obtained and he is started on an empiric antibiotic. Cultures return positive for methicillin-sensitive Staphylococcus aureus and his antibiotics are narrowed to intravenous oxacillin. (Osteomyelitis) Introduction Medications login to view 3 more bullets Mechanism of action login to view 4 more bullets Mechanism of resistance login to view 2 more bullets Clinical use login to view 1 more bullet Adverse effects login to view 2 more bullets