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Updated: Nov 22 2019

Aerobes and Anaerobes

5.0

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Images
https://upload.medbullets.com/topic/104008/images/aerophilic.jpg
  • Overview
    • Aerobes ("Nagging Pests Must Breathe")
      • Nocardia
      • Pseudomonas
      • Mycobacteria
        • explains TB's preference for the apices of the lung (highest PO2)
      • Bacillus
      • Bordatella
    • Anaerobes ("ABC")
      • Actinomyces
      • Bacteroides
      • Clostridium
    • Microaerophilic ("a bit of air for 'bacter")
      • Campylobacter
      • Helicobacter
      • Borrelia burgdorferi
    • Facultative anaerobes
      • Lactobacillus
      • most other bacteria!
  • Physiology
    • Aerobes
      • depend on O2 to generate ATP
    • Anaerobes
      • normal in GI tract but otherwise pathogenic
      • lack catalase and/or superoxide dismutase
        • more susceptible to oxidative damage
      • foul-smelling
        • due to short-chain fatty acids
      • hard to culture
      • produce gas in tissue
      • "aminO2glycosides" are ineffective against anaerobes
        • because these antibiotics require O2 to enter bacterial cell
    • Microaerophilic
      • requires oxygen, but requires low levels of oxygen
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