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Updated: Jul 6 2021

Viral Genetics

4.4

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Images
https://upload.medbullets.com/topic/104085/images/influenza-h1n1-reassortment.jpg
  • Overview
    • Recombination
      • exchange of genes between 2 chromosomes
      • crossing over occurs in homologous regions
    • Reassortment
      • viruses with segmented genomes exchange segments
      • analagous to high-frequency recombination
      • results in influenza pandemics
    • Complementation
      • 2 viruses infect a cell, but one is mutated and has a non-functional protein
      • the nonmutated virus helps the mutant by making protein for both viruses
    • Phenotypic mixing
      • 2 viruses infect a cell
      • virus A has its own genetic material, but the surface proteins of virus B
      • progeny viruses contain coat components and genetic material from virus A
        • this is because they only had the genetic material from virus A
      • genetic material is not altered
      • pseudovirion formation
        • when a virus's coat is entirely from another virus
        • nucleic acid and coat are completely mismatched
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