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Updated: Feb 12 2018

Introduction to Fungus-Like Bacteria

  • Introduction
    • Actinomyces and Nocardia are the fungus-like bacteria
      • they grow in branching structures (mycelia)
      • they are water and soil saprophytes
      • both are gram-positive rods
    • Actinomyces form sulfur granules and are anaerobic
    • Nocardia are acid-fast (partially) and aerobic
    • Treat with "SNAP"
      • Sulfa for Nocardia
      • Actinomyces use Penicillin
    • Characteristics

      Culture requirements
      • Aerobic
      • Anaerobe
      • Partially acid-fast
      • Not acid-fast


      • Soil
      • Commensal of mouth genital and GI tracts
      Clinical presentation
      • Pulmonary infections in immunocompromised
      • Cutaneuous infections in immunocompetent following trauma
      • Multiple brain abscesses
      • Cervico-facial abscesses which drain through sinus tracts formingyellow sulfur granules
      • PID with IUDs
      • Solitary brain abscess
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