Snapshot A 35-year-old woman presents to the urgent care clinic for genital ulcers. Her past medical history includes peptic ulcer disease and depression. She started having unprotected sexual intercourse with a new partner 1 month ago. She reports that he had not been tested for sexually transmitted diseases. She reports having a painful ulcer on her labia and wishes to be tested. On physical exam, there is a 1 cm ulcer with an erythematous base and irregular borders. When scraped, the ulcer easily bleeds. Introduction Classification login to view 6 more bullets Epidemiology login to view 7 more bullets Associated conditions login to view 1 more bullet Prevention login to view 1 more bullet Prognosis login to view 1 more bullet Presentation Symptoms login to view 2 more bullets Physical exam login to view 5 more bullets Studies Labs login to view 2 more bullets Making the diagnosis login to view 1 more bullet Differential Treponema pallidum primary infection login to view 2 more bullets Herpes login to view 2 more bullets Treatment Medical login to view 4 more bullets Complications Increased risk of HIV transmission Secondary bacterial infections