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Updated: Oct 18 2016

Drug Resistance

  • Overview
    • Penicillin
      • Campylobacter jejuni
      • Enterococcus faecalis
      • Neisseria gonorrohoeae
      • Gram-negative bacilli
        • resistant to benzylpenicillin G
        • outer membrane layer inhibits entry of penicillin G
        • may be susceptible to penicillin derivatives (e.g. ampicillin)
    • Ampicillin
      • Shigella
    • Vancomycin
      • Enterococcus faecalis (vancomycin resistant strains, VRE)
      • VRSA
      • Gram-negative bacilli
        • outer membrane layer inhibits entry of vancomycin
    • Methicillin
      • MRSA
        • via penicillin-binding protein mutation
    • Bacitracin
      • Streptococcus agalacticae
    • Optochin
      • Viridans group Streptococci
    • Ceftriaxone
      • some strains of Streptococcus pneumoniae
    • Amantadine/rimantadine
      • influenza virus
    • Isoniazid + rifampin
      • multi-drug resistant tuberculosis
    • Aminoglycosides
      • do not work against obligate anaerobes
      • aminoglycosides require O2 to enter the cell
    • Chloroquine
      • chloroquine-resistant Plasmodium falciparum malaria
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