Snapshot A 33-year-old man presents to his primary care physician for a cough and generalized malaise. His symptoms are associated with 2 episodes of mild hemoptysis and night sweats. He denies any sick contacts or recent travels; however, he states he was released from prison 4 months ago. Physical examination is unremarkable. A chest radiograph is obtained, which demonstrates pulmonary infiltrates and cavitations in the upper lobe. Introduction Classification login to view 1 more bullet Epidemiology login to view 4 more bullets Transmission login to view 1 more bullet Microbiology login to view 13 more bullets Pathogenesis login to view 7 more bullets Presentation TB can lead to pulmonary and extrapulmonary manifestations login to view 7 more bullets Symptoms login to view 6 more bullets Physical exam login to view 4 more bullets Imaging Chest radiograph login to view 8 more bullets Studies Sputum acid-fast testing login to view 1 more bullet Real-time nucleic acid amplification login to view 1 more bullet Tuberculin skin test (TST) login to view 10 more bullets Interferon-γ release assay login to view 2 more bullets Differential Lung cancer login to view 2 more bullets Treatment Medical login to view 12 more bullets Complications Pott disease Miliary or disseminated TB Meningitis Pericarditis Lymphadenitis Adrenal insufficiency