Snapshot A 35-year-old man presents to his primary care physician for worsening abdominal pain and "yellowing" of the skin. He reports that his symptoms began a few weeks ago and is associated with pale stools and dark urine. He denies any sick contacts and cannot identify a likely cause of his symptoms. He endorses to using opiates use via injection and is sexually active with multiple men and inconsistently using condoms. On physical exam, scleral icterus is appreciated in an uncomfortable appearing man. Abdominal exam is notable for tenderness to palpation in the right upper quadrant with mild hepatomegaly. Laboratory testing is notable for elevated aspartate and alanine aminotransferases and HCV RNA and anti-HCV antibody levels. Introduction Classification login to view 2 more bullets Epidemiology login to view 6 more bullets Pathogenesis login to view 3 more bullets Associated conditions login to view 9 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 4 more bullets Physical exam login to view 3 more bullets Studies Serologic studies login to view 3 more bullets Differential Hepatitis A infection login to view 2 more bullets Hepatitis B infection login to view 2 more bullets Treatment Medical login to view 12 more bullets Complications Advanced hepatic fibrosis Cirrhosis Hepatic decompensation Hepatocellular carcinoma