Snapshot A 45-year-old man presents to the emergency room after stepping on a nail resulting in a puncture wound on his right foot. He was given a tetanus booster and he left against medical advice refusing antibiotics. Two days later, he returned to the emergency room for increasing pain in his right foot. Physical exam reveals dark purple and black discoloration of the right sole with multiple ruptured bullae oozing serous drainage. On palpation, there is soft tissue crepitus. A wound culture is sent, which shows gram-positive bacilli. He is started on the appropriate antibiotics immediately. Introduction Classification login to view 7 more bullets Epidemiology login to view 13 more bullets Pathogenesis login to view 5 more bullets Prognosis login to view 2 more bullets Presentation Food poisoning login to view 2 more bullets Gas gangrene login to view 5 more bullets Imaging Computed tomography (CT) login to view 4 more bullets Studies Wound culture and Gram stain login to view 3 more bullets Clostridium assay login to view 1 more bullet Making the diagnosis login to view 1 more bullet Differential Cellulitis login to view 2 more bullets Treatment Management approach login to view 2 more bullets Medical login to view 8 more bullets Operative login to view 3 more bullets Complications Gas gangrene login to view 2 more bullets