Snapshot A 33-year-old man presents to the emergency department for fever, headache, and rash. His symptoms are accompanied by myalgias and malaise and began approximately 3 days ago. He returned from a trip in North Carolina, where he believes he was bitten by a tick. He has no significant past medical history. He is severely allergic to penicillin and doxycycline. Physical examination is notable for a blanching erythematous rash with macules on the wrist and ankles. He is started on chloramphenicol. (Rocky Mountain spotted fever) Introduction Mechanism of action login to view 3 more bullets Mechanism of resistance login to view 1 more bullet Clinical use login to view 3 more bullets Adverse events login to view 4 more bullets