Updated: 8/25/2020

ToRCHeS Infections

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Introduction
  • Infections that cross the placenta ("ToRCHeS")
    • Toxoplasma gondii 
    • Rubella
    • Cytomegalovirus (CMV)
    • HIV
    • Herpes simplex virus (HSV)
      • HSV-2 is more common, although HSV-1 is also possible
    • Syphilis
  • Signs in the fetus in ToRCHeS infections (nonspecific, common to multiple infections)
    • hepatosplenomegaly
    • fever
    • poor feeding
    • growth retardation
    • jaundice
    • thrombocytopenia
    • hearing impairment
    • mental retardation
    • autism
    • death
Other infections that cross the placenta
  • These infections can also cross the placenta
    • coxsackie B virus
    • poliovirus
    • parvovirus B19
    • Zika virus
    • Listeria monocytogenes
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