Snapshot A 40-year-old man with a past medical history of HIV presents to the clinic for follow-up. He reports that he has had difficulty swallowing, fevers and chills, nausea, vomiting, and abdominal pain. He reports that he has been compliant with his HIV medications. On physical exam, he has ulcers in his oropharynx. His laboratory tests reveal positive CMV-specific immunoglobulin G but negative heterophile antibodies. He is given an antiviral treatment and is admitted for an endoscopy workup and close monitoring. (CMV esophagitis) Introduction Classification login to view 4 more bullets Epidemiology login to view 9 more bullets Pathogenesis login to view 3 more bullets Associated conditions login to view 10 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 13 more bullets Physical exam login to view 4 more bullets Studies Labs login to view 9 more bullets Histology login to view 2 more bullets Making the diagnosis login to view 1 more bullet Differential Epstein-Barr viral (EBV) mononucleosis login to view 3 more bullets Treatment Management approach login to view 1 more bullet Conservative login to view 5 more bullets Medical login to view 7 more bullets Complications Thrombosis Colitis Permanent vision changes