Snapshot A 65-year-old man presents to the emergency department with a headache, nausea, and altered mental status. His symptoms developed a few days ago and have since worsened. He was recently diagnosed with normal-pressure hydrocephalus and had placement of a ventriculoperitoneal shunt. Physical examination is notable for diffuse abdominal pain. Direct aspiration of the cerebral spinal fluid shunt is obtained, and CSF analysis demonstrates a leukocytosis, elevated protein, and decreased glucose. CSF Gram stain demonstrates gram-positive cocci in clusters. CSF cultures are pending. Preparations are made for removal of the shunt and he is started on vancomycin and ceftazidime. Introduction Classification login to view 2 more bullets Reservoir login to view 2 more bullets Pathogenesis login to view 3 more bullets Associated conditions login to view 2 more bullets Presentation Symptoms/physical exam login to view 3 more bullets Treatment Conservative login to view 6 more bullets Medical login to view 7 more bullets Complications Sepsis Prosthetic valve endocarditis Meningitis Exit site signs of infections login to view 2 more bullets