Snapshot A 35-year-old presents to the emergency department due to abdominal pain and malaise. He also reports "yellow-ing" of his skin. Medical history is noncontributory. Social history is notable for intravenous drug use and having multiple sexual partners. Physical examination is remarkable for right upper quadrant tenderness, generalized jaundice, and scleral icterus. Laboratory studies demonstrate the presence of HBsAg and significantly elevated IgM anti-HBc, and HBeAg. Introduction Classification login to view 2 more bullets Epidemiology login to view 5 more bullets Transmission login to view 5 more bullets Pathogenesis login to view 6 more bullets Prognosis login to view 4 more bullets Presentation Symptoms login to view 7 more bullets Physical exam login to view 12 more bullets Studies Liver function tests login to view 3 more bullets Serologic studies login to view 16 more bullets Differential Hepatitis A infection login to view 2 more bullets Hepatitis C infection login to view 2 more bullets Treatment Medical login to view 20 more bullets Complications Superinfection with hepatitis D virus Acute fulminant hepatic failure Cirrhosis Hepatocellular carcinoma