Overview Introduction cellular structural protein with a hollow tubular structure Structure composed of polymerized dimers of α- and β-tubulin each dimer has 2 GTP molecules bound constant assembly (slow) and disassembly (fast) clinical importance login to view 10 more bullets Function component of many important cellular structures cilia login to view 18 more bullets mitotic spindles molecular motor proteins login to view 11 more bullets Pharmacologic importance mebendazole class: antihelminthic mechanism of action login to view 1 more bullet griseofulvin class: antifungal mechanism of action login to view 1 more bullet uses login to view 1 more bullet vincristine/vinblastine class: anti-cancer mechanism of action login to view 2 more bullets side effects login to view 3 more bullets paclitaxel (taxol) class: anti-breast cancer mechanism login to view 2 more bullets colchicine class: anti-gout mechanism of action login to view 3 more bullets