Overview Snapshot A 50-year-old woman presents to her primary care physician for a regular checkup. She states that for the past four months she has not experienced menses. Her primary care physician suspects that she has gone through menopause. On routine lab work, her LDL has increased as compared to one year ago, and her HDL has decreased drastically. Introduction Mechanisms for fatty acid and cholesterol transport Different types that vary by density login to view 7 more bullets types of apolipoprotein HDL Function transfer cholesterol login to view 1 more bullet good cholesterol Structure apoA-1 login to view 1 more bullet apoE/apoC-II login to view 1 more bullet LDL Function transfer cholesterol login to view 2 more bullets bad cholesterol Structure apoB-100 login to view 1 more bullet IDL Function VLDL → IDL + TGs picks up cholesterol esters from HDL login to view 2 more bullets Structure apoE login to view 3 more bullets apoB-100 login to view 1 more bullet VLDL Function transports TGs login to view 1 more bullet Structure apoB-100 login to view 1 more bullet apoC-II login to view 3 more bullets apoE login to view 1 more bullet Chylomicrons Function transport cholesterol, TGs, FAs, and fat soluble vitamins login to view 1 more bullet released from intestinal lumen cells into lymphatics Structure apo-48 login to view 1 more bullet apoC-II login to view 2 more bullets apoE login to view 2 more bullets