Overview Other names Krebs cycle, tricarboxylic acid (TCA) cycle Function generate high amounts of NADH/FADH2 that act as fuel for ATP synthesis in the electron transport chain Pathway occurs in the mitochondria requires O2 to function net equation acetyl-CoA + 3 NAD+ + FAD + GDP + Pi → 2CO2 + 3 NADH + FADH2 + GTP + CoA login to view 4 more bullets Important enzymes isocitrate dehydrogenase login to view 4 more bullets α-ketoglutarate dehydrogenase complex login to view 8 more bullets succinyl-CoA synthetase login to view 1 more bullet succinate dehydrogenase login to view 1 more bullet important intermediates citrate login to view 2 more bullets succinyl-CoA login to view 1 more bullet fumarate login to view 1 more bullet malate login to view 1 more bullet Regulation energy status control NO hormonal control