Overview Sodium/glucose cotransporter (SGLT) function transport glucose actively across lumen against concentration gradient login to view 1 more bullet location small intestine (SGLT1) login to view 1 more bullet proximal tubule of nephron (SGLT2) login to view 1 more bullet Glucose transporters (GLUT) function facilitated diffusion of glucose down concentration gradients login to view 1 more bullet divided into many subtypes that localize to different tissues GLUT-1 function basal glucose uptake login to view 3 more bullets location wide distribution in tissues in the body (brain, erythrocytes, endothelial cells, cornea etc.) GLUT-2 function low affinity glucose uptake login to view 3 more bullets location hepatocytes pancreatic β-cells kidney small intestines GLUT-3 function high affinity glucose uptake login to view 1 more bullet location brain neurons GLUT-4 function insulin-controlled uptake of glucose basal level of glucose intake without insulin login to view 3 more bullets location adipocytes myocytes cardiomyocytes