Updated: 3/1/2017

Microarrays

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Overview
  • Function 
    • can probe for thousands of different mRNAs simultaneously
  • Process
    • a chip has thousands of DNA sequences robotically attached on a grid
    • a solution of degraded mRNA is added to the chip
    • thousands of probes are added
    • a computer analyzes the degree of binding to various regions of the chip
  • Clinical use 
    • analyze cancer cell gene expression
      • can determine probability of becoming malignant based on population comparison studies
      • can be used to guide therapy
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