Updated: 11/8/2016

Microfilaments

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  • Overview
    • Examples
      • actin
    • Structure
      • helical polymers of G-actin
        • has polarity
          • + end is site of formation
          • - end is site of degradation
      • "treadmilling"
        • formation requires ATP
        • dynamic structure that is constantly forming and breaking down
          • can sample environment
        • G-actin has intrinsic ATPase capabilities
    • Function
      • can interact with myosin to
        • mediate contractile forces
        • mediate motile forces
        • mediate cytokinesis
      • can interact with cell membrane to
        • form core of microvilli
          • function to increase absorptive surface area
        • anchor tight junctions
        • anchor zonula adherens

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