Updated: 11/8/2016

Microfilaments

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Overview
  • Examples
    • actin
  • Structure
    • helical polymers of G-actin
      • has polarity
        • + end is site of formation
        • - end is site of degradation
    • "treadmilling"
      • formation requires ATP
      • dynamic structure that is constantly forming and breaking down
        • can sample environment
      • G-actin has intrinsic ATPase capabilities
  • Function
    • can interact with myosin to
      • mediate contractile forces
      • mediate motile forces
      • mediate cytokinesis
    • can interact with cell membrane to
      • form core of microvilli
        • function to increase absorptive surface area
      • anchor tight junctions
      • anchor zonula adherens
 

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