Structure Stacks of cisternae Associated with membrane bound vesicles Two faces cis receiving face from the ER input to the Golgi convex shape trans exports away from Golgi location of trans-Golgi network faces plasma membrane concave shape Function Post-translational peptide modification addition of N-oligosaccharides on asparagine (amino-group) O-oligosaccharides on serine and threonine (hydroxyl-group) mannose-6-phosphate designates transport to lysosome deficient in I-cell disease see Lysosome topic sulfation of tyrosines cleavage of propeptides peptidase cleaves proinsulin to insulin + C-peptide deficient in hyperproinsulinemia presents similar to NIDDM Packaging/distribution of proteins and lipids received from ER (adds amino acid residues that golgi later modifies) via coat protein complex (COP) II this protein initiates budding process RER→ cis-Golgi = anterograde anterograde movement mediated by COP II Golgi → ER = retrograde retrograde movement mediated by COP I leaves Golgi headed towards several destinations plasma membrane lysosomes secretory vesicles mediated by clathrin Proteoglycan assembly sulfation of sugars
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All Videos (1) Login to View Community Videos Login to View Community Videos Golgi apparatus Chris Robinson Biochemistry - Golgi Apparatus D 2/11/2015 318 views 4.8 (8)