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Updated: 3/2/2023

Kwashiorkor and Marasmus

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  • Kwashiorkor
    • Causes
      • protein-deficient diet
    • Presentation
      • skin lesions
      • pitting edema
        • ↓ albumin leads to ↓ oncotic pressure in vasculature and loss of fluid into extravascular space
      • ascites
      • liver malfunction
        • ↓ apolipoprotein synthesis
        • fatty liver
      • defects in cell-mediated immunity
        • ↓ in complement protein synthesis
      • muscle protein relatively unchanged
  • Marasmus
    • Causes
      • protein- and caloric-deficient diet
    • Presentation
      • tissue and muscle wasting
        • "broomstick" extremities
        • breakdown of muscle protein for energy
      • loss of subcutaneous fat
      • variable edema

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