Updated: 4/18/2017

Kwashiorkor and Marasmus

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Kwashiorkor
  • Causes
    • protein-deficient diet
  • Presentation
    • skin lesions
    • pitting edema 
      • ↓ albumin leads to ↓ oncotic pressure in vasculature and loss of fluid into extravascular space
    • ascites
    • liver malfunction
      • ↓ apolipoprotein synthesis
      • fatty liver
    • defects in cell-mediated immunity
      • ↓ in complement protein synthesis
    • muscle protein relatively unchanged
Marasmus
  • Causes
    • protein- and caloric-deficient diet
  • Presentation
    • tissue and muscle wasting
      • "broomstick" extremities
      • breakdown of muscle protein for energy
    • loss of subcutaneous fat
    • variable edema
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