Overview Covalent alterations phosphorylation kinase additions of phosphate groups glycosylation addition of oligosaccharide signals for translocation into ER/Golgi hydroxylation allows for ↑ in hydrogen bonding needed for collagen synthesis γ-carboxylation addition of carboxyl group allows for Ca2+ binding site needed for several clotting factors prenylation addition of farnesyl or geranylgeranyl lipid groups signals for membrane insertion Proteolysis cleavage of N- or C- terminal propeptides peptides beginning in "pro-" converts zymogens to mature enzymes examples enzymes ending in "-ogen"
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All Videos (1) Login to View Community Videos Login to View Community Videos Protein Posttranslation Modifications Biochemistry - Post-Translational Modification D 2/14/2015 100 views 5.0 (3)