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A 17-year-old male African immigrant visits his primary care physician with a mass on the right side of his jaw. He denies drug or alcohol use and does not take any medication. Serology for Epstein-Barr Virus (EBV) infection is positive. A biopsy of the lesion is taken and shown in Figure A. Which of the following chromosomal translocations is most likely present in this tissue?
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A 40-year-old male presents to his primary care physician for a regularly scheduled check-up. Physical examination reveals nontender cervical lymphadenopathy. A biopsy of the lymph node reveals aggregates of follicular architecture, and cytogenic analysis shows a t(14;18) translocation. The protein most likely responsible for the patient’s condition does which of the following:
Regulates passage through the cell cycle
Activates DNA repair proteins
Provides mitotic cytoskeleton
Regulates cell growth through signal transduction