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Updated: Sep 4 2021

Hodgkin vs. Non-Hodgkin Lymphoma

  • Overview
    • There are many key differences between Hodgkin's and Non-Hodgkin's lymphoma
      • see individual topics
        • Hodgkin lymphoma
        • non-Hodgkin lymphoma
      • Hodgkin vs. Non-Hodgkin Lymphoma
      • Characteristics
      • Hodgkin
      • Non-Hodgkin
      • Cells involved
      • Reed-Sternberg Cells
      • B or T cells
      • Mass composition
      • Localized, single group of nodes
      • Extranodal spread is rare
      • Peripheral, multiple nodes
      • Often extranodal
      • Pattern of spread
      • Contiguous spread
      • Non-contiguous spread
      • Symptoms
      • Commonly with B symptoms,low-grade fever, night sweats, weight loss
      • Fewer constitutional symptoms
      • Leukemicphase
      • No
      • Yes
      • Associations
      • Associated with EBV (50%)
      • Seen more often with HIV/immunosuppression
      • Epidemiology- age distribution
      • Bimodal distribution (young adults and 50s-60s)
      • Peak incidence 20-40 years
      • Epidemiology - sex preference
      • More common in men
      • No difference
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