Updated: 3/6/2018

Hodgkin vs. Non-Hodgkin Lymphoma

Review Topic
  • There are many key differences between Hodgkin's and Non-Hodgkin's lymphoma
    • see individual topics
      • Hodgkin lymphoma
      • non-Hodgkin lymphoma
Characteristics  Hodgkin Non-Hodgkin
  • Cells involved
  • Reed-Sternberg Cells
  • B or T cells
  • Mass composition
  • Localized, single group of nodes
  • Extranodal spread is rare
  • Peripheral, multiple nodes
  • Often extranodal
  • Pattern of spread
  • Contiguous spread
  • Non-contiguous spread
  • Symptoms
  • Commonly with B symptoms, low-grade fever, night sweats, weight loss
  • Fewer constitutional symptoms
  • Leukemic phase
  • No
  • Yes
  • Associations
  • Associated with EBV (50%)
  • Seen more often with HIV/immunosuppression
  • Epidemiology - age distribution
  • Bimodal distribution (young adults and 50s-60s)
  • Peak incidence 20-40 years
  • Epidemiology - sex preference
  • More common in men
  • No difference

Please rate topic.

Average 5.0 of 8 Ratings

Thank you for rating! Please vote below and help us build the most advanced adaptive learning platform in medicine

The complexity of this topic is appropriate for?
How important is this topic for board examinations?
How important is this topic for clinical practice?
Topic COMMENTS (11)
Private Note