Overview Mechanism login to view 6 more bullets Examples Tumor Suppressor Genes Gene Associated Tumor Chromosome APC Colorectal cancer (associated with FAP) 5 p16 Melanoma 9 WT1 Wilms' tumor 11 Rb Retinoblastoma and osteosarcoma 13 BRCA2 Breast cancer 13 NF1 Neurofibromatosis type 1 17 BRCA1 Breast and ovarian cancer 17 TP53 Most human cancers and Li-Fraumeni syndrome 17 DPC Pancreatic cancer (stands for deleted in pancreatic cancer) 18 DCC Colon cancer (stands for deleted in colon cancer) 18 NF2 Neurofibromatosis type 2 22