Snapshot A 69-year-old woman presents to her primary care physician with complaint of chest discomfort. She describes having shortness of breath and is easily fatigued by routine activities. At the clinic, she is alarmed to see that her weight has dropped more than 10 pounds since she last weighed herself. She has no prior history of smoking. A chest radiograph is obtained and is shown in the image. Introduction Overview login to view 1 more bullet Epidemiology login to view 11 more bullets Prognosis login to view 2 more bullets Presentation Symptoms login to view 6 more bullets Physical exam login to view 1 more bullet Imaging Chest radiograph login to view 4 more bullets CT or MRI of chest login to view 2 more bullets Studies Thoracentesis login to view 2 more bullets Pleural biopsy login to view 7 more bullets Differential Non-small cell lung cancer login to view 2 more bullets Small cell lung cancer login to view 2 more bullets Treatment Medical login to view 6 more bullets Surgical login to view 2 more bullets