Snapshot A 52-year-old woman with fair skin is concerned about a pink pearly lesion that is growing slowly on her cheek. She is a varsity water polo coach at her local high school and spends many hours under the sun. She admits to not using sunscreen consistently. Introduction Most common skin malignancy that rarely, if ever, metastasizes Epidemiology login to view 5 more bullets Commonly affects upper lip (squamous cell carcinoma typically affects lower lip) Presentation Physical exam login to view 5 more bullets Evaluation Diagnosis by skin biopsy login to view 2 more bullets Differential Squamous cell carcinoma Actinic keratosis Treatment Determined by size, location, and cosmetic considerations Surgical excision Mohs surgery login to view 1 more bullet Prognosis, Prevention, and Complications Prognosis login to view 2 more bullets Prevention login to view 2 more bullets