Snapshot Squamous cell carcinomas appear as reddish, ulcerative lesions A 70-year-old man presents to the dermatologist’s office for his annual skin exam. He complains of a large pink lesion on his cheek that oozes and bleeds. It never seemed to heal properly. He is concerned, because he knows that he should have used more sunscreen throughout his life. Introduction Invasive primary skin malignancy arising from keratinocytes of skin or mucosa Epidemiology login to view 11 more bullets Pathogenesis login to view 2 more bullets Keratoacanthoma is a variant of low-grade squamous cell carcinoma login to view 1 more bullet Presentation Symptoms login to view 1 more bullet Physical exam login to view 6 more bullets Evaluation Diagnosis by skin biopsy login to view 3 more bullets Differential Diagnosis Actinic keratosis Actinic cheilitis Treatment Surgical login to view 1 more bullet Prognosis, Prevention, and Complications Prognosis login to view 1 more bullet Prevention login to view 2 more bullets