Snapshot hairy cells A 50-year-old man presents to his primary care physician for an annual visit. He has no complaints. His past medical history includes hypertension, hypercholesterolemia, and rheumatoid arthritis. He goes for routine blood tests today, which reveals marked pancytopenia. A peripheral blood smear is done, showing cells with hair-like projections. Introduction Indolent leukemia of mature B-cells with infiltration of bone marrow and spleen Epidemiology login to view 2 more bullets Associated conditions login to view 1 more bullet Characteristics login to view 2 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 5 more bullets Physical exam login to view 2 more bullets Evaluation Peripheral blood smear login to view 2 more bullets Flow cytometry login to view 2 more bullets Bone marrow aspirate login to view 1 more bullet CBC login to view 3 more bullets Differential Diagnosis Non-Hodgkin lymphoma Mantle cell lymphoma Treatment Purine analogs login to view 4 more bullets Complications Complications login to view 2 more bullets