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An ill-appearing 70-year-old male smoker presents to your office at 4:00 p.m. The left panel of Figure A shows the patient's appearance when he wakes up in the morning and the right panel shows the patient as he appears after walking around during the day. He complains of dyspnea and cough for several weeks, and on examination you also note his distended neck veins. What is the most likely cause of this patient's illness?
Congestive heart failure
Pancoast tumor (bronchogenic carcinoma)
ACE inhibitor therapy
Type I hypersensitivity reaction
Subclavian steal syndrome
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A lung mass of a 50 pack-year smoker is biopsied. If ADH levels were grossly increased, what would most likely be the histologic appearance of this mass?
Tall columnar cells bordering the alveolar septum
Sheets of small round cells with hyperchromatic nuclei
Layered squamous cells with keratin pearls
Hyperplasia of mucin producing glandular tissue
Pleomorphic giant cells with leukocyte fragments in cytoplasm
A 55-year-old male smoker presents to your office with hemoptysis, central obesity, and a round face with a "moon-like" appearance. He is found to have a neoplasm near the hilum of his left lung. A biopsy of the tumor reveals small basophilic cells with finely granular nuclear chromatin (a "salt and pepper" pattern). Which of the following is the most appropriate treatment for this patient?
Cisplatin and radiotherapy
A 54-year-old female is admitted to the hospital for progressive exertional dyspnea and cough productive of tan-colored liquid for 6 months. She has never smoked a day in her life. A lung biopsy is shown in Figure A that demonstrates tall, columnar cells that line the alveoli septa. The most likely diagnosis for this patient is:
Squamous cell carcinoma
Small cell carcinoma
Metastatic breast cancer