Lipoma Introduction most common benign soft tissue tumor in adults soft, well-encapsulated fat tumor Differential diagnosis ganglion cysts synovial herniation over underlying tendon sheath or joint dorsal wrist commonly affected, but volar wrist can also be affected asymptomatic, painless transilluminates with light distinguishes ganglion cysts from solid masses such as lipomas Treatment simple excision typically curative Liposarcoma Introduction most common malignant soft tissue tumor in adults malignant fat tumor that can be large Evaluation lipoblast is the characteristic cell Treatment will recur without full excision Rhabdomyoma Introduction benign tumor derived from striated muscle (skeletal or cardiac) most common cardiac tumor in children associated conditions tuberous sclerosis specifically rhabdomyoma of the heart Rhabdomyosarcoma Introduction most common malignant soft tissue tumor of childhood arises from skeletal muscle progenitors typically involves head/neck, vagina Evaluation rhabdomyoblast is characteristic cell desmin positive stains