Updated: 4/5/2022

Soft Tissue Tumors

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Lipoma
  • Introduction
    • most common benign soft tissue tumor in adults
    • soft, well-encapsulated fat tumor
  • Differential diagnosis
    • ganglion cysts
      • synovial herniation over underlying tendon sheath or joint 
      • dorsal wrist commonly affected, but volar wrist can also be affected
      • asymptomatic, painless
      • transilluminates with light
        • distinguishes ganglion cysts from solid masses such as lipomas
  • Treatment
    • simple excision typically curative
Liposarcoma
  • Introduction
    • most common malignant soft tissue tumor in adults
    • malignant fat tumor that can be large
  • Evaluation 
    • lipoblast is the characteristic cell
  • Treatment
    • will recur without full excision
Rhabdomyoma
  • Introduction
    • benign tumor derived from striated muscle (skeletal or cardiac)
      • most common cardiac tumor in children 
    • associated conditions
      • tuberous sclerosis 
        • specifically rhabdomyoma of the heart
Rhabdomyosarcoma
  • Introduction
    • most common malignant soft tissue tumor of childhood
    • arises from skeletal muscle
    • typically involves head/neck, vagina
  • Evaluation
    • rhabdomyoblast is characteristic cell
      • desmin positive stains

 

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