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A 70-year-old female presents to your office with nausea, vomiting, and 3 months of weight loss. On physical exam, you observe a finding seen in Figure A. You suspect adenocarcinoma, and you immediately order a biopsy to ascertain the extent of metastatic disease. In which of the following organs would you observe the primary tumor with abundant mucus and signet ring cells on biopsy if metastatic disease were present?
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A 60-year-old Japanese male presents to your office with epigastric pain following 1 month of unintentional weight loss. He reports that he has followed a strict diet of low-fat smoked fish all his life. On physical exam, you note a skin finding similar to Figure A. If this patient undergoes aggressive surgical treatment, which of the following may result?
Increased prothrombin time
Acute cellular rejection
Esophageal squamous cell carcinoma