Updated: 2/13/2018

Paraneoplastic Effects of Tumors

Topic
Review Topic
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Overview
 
Neoplasm
Potential Tumor Products
Presentation
Small cell lung carcinoma ACTH, ADH, and Antibodies against presynaptic Ca2+ channels at neuromuscular junction Cushing's syndrome , SIADH , and Lambert-Eaton syndrome
Squamous cell lung carcinoma PTH-related peptide, TGF-β, TNF, and IL-1 Hypercalcemia
Renal cell carcinoma Erythropoietin Polycythemia
Thymoma Antibodies against post-synaptic Ach receptor Myasthenia gravis
Hemangioblastoma Erythropoietin Polycythemia
Intracranial neoplasm ADH SIADH
Breast carcinoma PTH-related peptide, TGF-β, TNF, and IL-1 Hypercalcemia
Leukemias and lymphomas Excess nucleic acid turnover Gout and urate nephropathy
 

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