Snapshot A 65-year-old-male presents with complaints of epigastric pain and belching, which improves when he eats food but gets worse within a few hours after his meal. The pain is described as stabbing, intermittent, and concentrated at the epigastric region. He noticed a 5-lb. weight loss over the past 3 months and a dark color to his stools. Calcium carbonate seems to help with the pain. Introduction Clinical definition login to view 11 more bullets Epidemiology login to view 9 more bullets Pathogenesis login to view 14 more bullets Associated conditions login to view 4 more bullets Painful sores or ulcers in the lining of the stomach or duodenum login to view 1 more bullet Occurs when gastric acid secretion outweighs mucosal defenses login to view 6 more bullets Presentation Symptoms login to view 9 more bullets Physical exam login to view 2 more bullets Imaging Esophagogastroduodenoscopy (EGD) login to view 4 more bullets Abdominal and chest radiographs login to view 2 more bullets Studies Urease breath test login to view 2 more bullets Complete blood count login to view 1 more bullet Differential Gastric malignancy login to view 2 more bullets Chronic pancreatitis login to view 2 more bullets Treatment Management depends on disease etiology and severity Lifestyle login to view 1 more bullet H. pylori induced PUD login to view 2 more bullets NSAID-induced PUD login to view 2 more bullets Bleeding ulcers login to view 3 more bullets Surgery login to view 3 more bullets Complications Bleeding Perforation login to view 3 more bullets Obstruction Malignancy