Snapshot A 66-year-old man presents to the clinic with chronic weakness. He reports some shortness of breath with exercises, when he has never experienced before. He denies any fever, chest pain but does endorse lightheadedness and some dark colored stool. Laboratory studies demonstrate mild iron deficiency anemia. A colonoscopy is performed and vascular abnormalities are noted in the GI tract. Introduction Clinical definition login to view 5 more bullets Epidemiology login to view 2 more bullets Pathogenesis login to view 4 more bullets Associated conditions login to view 7 more bullets Presentation Symptoms login to view 8 more bullets Physical exam login to view 3 more bullets Imaging Endoscopy login to view 4 more bullets Computed tomography (CT) angiography login to view 1 more bullet Angiography login to view 2 more bullets Studies Laboratory studies login to view 1 more bullet Intaoperative enteroscopy login to view 1 more bullet Differential Diverticulosis login to view 2 more bullets Colon/rectal cancer login to view 2 more bullets Treatment Treatment is dependent on the level bleeding, if the lesion is not actively bleeding or is discovered incidentally on screening colonoscopy, no treatment is needed First-line login to view 4 more bullets Second-line login to view 6 more bullets Third-line login to view 3 more bullets Complications Anemia Bleeding/hemorrhage Exsanguination