Snapshot A 2-day-old neonate is noted in the well-baby nursery to have some abdominal distention. He had one episode of bilious vomiting. He is feeding well and does not seem altered. However, his mom is concerned that he has not passed any stool yet. Abdominal radiography shows distended loops of bowel. A barium enema shows a dilated colon with a funnel-shaped transition zone. Pediatric surgery is consulted for biopsy and surgical correction. Introduction Congenital megacolon login to view 1 more bullet Pathogenesis login to view 4 more bullets Genetics login to view 1 more bullet Associated conditions login to view 3 more bullets Presentation Symptoms login to view 4 more bullets Physical exam login to view 3 more bullets Evaluation Gold standard diagnosis login to view 2 more bullets Imaging login to view 3 more bullets Differential Diagnosis Imperforate anus Functional constipation Intussusception Duodenal atresia Meconium ileus Treatment Supportive care Surgical resection Prognosis, Prevention, and Complications Prognosis login to view 3 more bullets Complications login to view 2 more bullets