Overview gout Snapshot A 50-year-old man presents 4 months after an acute gout flare to his primary care physician. Since then, he has had 2 more episodes of minor flares that resolved on its own. He reports wanting better control of this disease. His physician describes several options for chronic gout and suggests allopurinol as a good first-line option. Introduction Chronic gout drugs login to view 7 more bullets Acute gout drugs login to view 6 more bullets Drugs to avoid login to view 2 more bullets Allopurinol Mechanism of action login to view 1 more bullet Clinical use login to view 2 more bullets Toxicity login to view 3 more bullets Febuxostat Mechanism of action login to view 1 more bullet Clinical use login to view 1 more bullet Toxicity login to view 2 more bullets Pegloticase Mechanism of action login to view 2 more bullets Clinical use login to view 1 more bullet Toxicity login to view 2 more bullets Probenecid Mechanism of action login to view 1 more bullet Clinical use login to view 1 more bullet Toxicity login to view 5 more bullets Colchicine Mechanism of action login to view 1 more bullet Clinical use login to view 1 more bullet Toxicity login to view 1 more bullet