Omeprazole Other agents: lansoprazole and pantoprazole Mechanism irreversibly inhibits H+/K+-ATPase in gastric parietal cells H+/K+-ATPase is a primary active transporter Clinical use peptic ulcer disease well-documented in literature as most effective agent gastritis GERD Zollinger-Ellison syndrome Eradication of H. pylori Toxicity P-450 inhibitor
QUESTIONS 1 of 4 1 2 3 4 Previous Next Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK (M1.GI.13.3) A 37-year-old woman presents to your office with heartburn. Following an extensive workup, you diagnose her with a duodenal ulcer secondary to H. pylori infection. You prescribe triple therapy of omeprazole, clarithromycin, and amoxicillin. Which of the following best describes the mechanism of action of omeprazole? Tested Concept QID: 101060 Type & Select Correct Answer 1 SST2 receptor agonist 0% (0/140) 2 Parasympathetic inhibition 3% (4/140) 3 Reversible block of H2 receptors 21% (29/140) 4 Inhibition of primary active transport 71% (99/140) 5 Inhibition of 50S ribosomal subunit 4% (5/140) M 1 Question Complexity E Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 4 Review tested concept