Snapshot A 40-year-old obese woman presents to her family medicine doctor for intermittent abdominal pain for the past few months as well as fatigue. She has a past medical history of hyperlipidemia, diabetes, and hypertension. She has been trying to lose weight but has not been successful. She reports drinking alcohol socially, on average 2 times per month. On exam, she is not jaundiced and has no tenderness to palpation. Her liver is noted to be enlarged. Laboratory evaluation reveals mildly elevated liver enzymes, and she is referred for liver biopsy to confirm the diagnosis of nonalcoholic steatohepatitis. (Chronic hepatitis) Introduction Overview login to view 4 more bullets Epidemiology login to view 19 more bullets Pathogenesis login to view 3 more bullets Prognosis login to view 4 more bullets Presentation Acute hepatitis login to view 14 more bullets Chronic hepatitis login to view 9 more bullets Imaging Ultrasound of liver login to view 6 more bullets Studies Serum labs login to view 13 more bullets Serologic Findings Clinical Implications HBV surface antigen Anti-HBV core antibody Active infection Anti-HBV surface antigen antibody Immunity Anti-HBV core antibody Immunity HBV e-antigen Highly infectious HCV antibody Exposure Differential Gallbladder disease login to view 2 more bullets Treatment Management approach login to view 2 more bullets Medical login to view 19 more bullets Complications Hepatocellular carcinoma Cirrhosis