Updated: 5/17/2016

Oral Lesions in HIV

Topic
Review Topic
0
0
Introduction
  • Oral lesions in patients with HIV are common (30-80%) White corrugated plaque on left lateral tongue border
    • may indicate impairment in general health and poor prognosis
    • presence suggests low CD4+ count and high viral load
    • often an early marker of infection
    • may be infectious, neoplastic, or traumatic 
  • Infections
    • candidiasis
      • "oral thrush" infection from Candida yeast
      • soft white/yellow, curd-like plaques on the oral mucosa
        • can be scraped off leaving a red undersurface
      • prevalence as high as 95%
      • pre-AIDS defining lesion
    • hairy leukoplakia
      • infection of the tongue by EBV
      • asymtomatic, bilateral, vertically corrugated, or hairy white lesions on the lateral border of the tongue
    • herpes simplex virus
      • clusters of painful, small vesicles and ulcers on the palate or gingiva
  • Neoplastic
    • Kaposi's sarcoma
      • caused by HSV-8 infection
      • painless violaceous lesions, most commonly seen on hard palate or anterior gingival mucosa
    • non-Hodgkin's lymphoma
      • rapidly enlarging rubbery mass in the tonsillar fossa, palate, or gingiva
  • Other
    • apthous ulcers
      • "canker sores"
      • unknown origin, but may be viral or stress-induced
    • angular chelitis
      • red, ulcerated, and fissured lesions at the angles of the mouth
 

Please rate topic.

Average 4.3 of 4 Ratings

Thank you for rating! Please vote below and help us build the most advanced adaptive learning platform in medicine

The complexity of this topic is appropriate for?
How important is this topic for board examinations?
How important is this topic for clinical practice?
Topic COMMENTS (10)
Private Note