Updated: 5/29/2017

Anastrozole / Exemestane

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Questions
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Evidence
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Topic
Mechanism
  • Aromatase inhibitors
    • ↓ estrogen by inhibiting peripheral conversion of testosterone
Indications
  • Estrogen-receptor positive breast cancer
Toxicity
  • Menopausal symptoms

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Questions (1)

(M1.RP.12.66) A 65-year-old female is diagnosed with invasive ductal carcinoma of the breast. After a lumpectomy with a negative axillary lymph node dissection and subsequent radiation therapy, the patient is started on adjuvant chemotherapy with anastrozole. Which of the following is an expected side effect of this medication?

QID: 100367
1

Increased risk for endometrial carcinoma

21%

(108/521)

2

Decreased LDL and increased HDL levels

5%

(28/521)

3

Mental confusion progressing to more severe dementia

5%

(24/521)

4

Increased risk for osteoporosis

61%

(319/521)

5

Excessive weight loss

6%

(29/521)

M 3 D

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Evidence (1)
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