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Updated: 4/5/2018

Clomiphene

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  • Mechanism
    • Partial estrogen receptor agonist
      • See Female Hypothalamic-Pituitary Axis topic
    • Acts specifically in hypothalamus which antagonizes normal negative feedback inhibition
    • Results in an ↑ release of LH and FSH from pituitary
      • stimulates ovulation
  • Indications
    • Infertility
    • PCOS
  • Toxicity
    • Ovarian enlargement
    • Multiple birth pregnancy
    • Visual disturbances
    • Hot flashes

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Reproductive | Clomiphene
  • Reproductive
  • - Clomiphene

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