Updated: 5/1/2021

Leuprolide

0%
Topic
Review Topic
0
0
N/A
N/A
Questions
1
0
0
Topic
Mechanism
  • GnRH analog
    • See female hypothalamic-pituitary axis topic
    • See male hypothalamic-pituitary axis topic
  • Action depends on mode of administration 
    • GnRH antagonist when infusion continuously
      • causes initial increase in androgens after initial administration 
    • GnRH agonist when infused in a pulsatile manner
      • is the natural way the body releases GnRH
Indications
  • Infertility (pulsatile)
  • Prostate cancer (continuous)
    • coadministered with flutamide
  • Uterine fibroids
Toxicity
  • Antiandrogen side effects
  • Nausea
  • Vomiting

Please rate topic.

Average 4.5 of 4 Ratings

Questions (1)
Question locked
Sorry, this question is for
PEAK Premium Subscribers only
Upgrade to PEAK
EXPERT COMMENTS (4)
Private Note