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Updated: Nov 13 2020

Benign Breast Tumors

  • Snap Shot
    • A 28-year-old female presents with a 2 cm lump in the upper outer quadrant of her left breast. The mass changes in size in keeping with her menstrual cycle.
  • Introduction
    • Several types
      • fibroadenoma
        • most common tumor in women < 35
        • benign lesion that does not progress to breast cancer
        • size and tenderness varies with estrogen changes
        • histology shows hypercellular stroma that encircles or compresses ducts
      • intraductal papilloma
        • small tumor
        • typically beneath areola in lactiferous sinuses
        • common cause of bloody nipple discharge
        • histology shows proliferative glands with intact fibrovascular cores
      • phyllodes tumor
        • most common in post-menopausal women
        • consists of connective tissue and cysts with "leaf-like" projections
          • derived from stromal cells
        • may progress to malignancy
  • Presentation
    • Fibroadenoma
      • palpable as a small, mobile, well circumscribed and firm mass
    • Intraductal papilloma
      • serous or bloody nipple discharge
    • Phyllodes tumor
      • large, bulky mass
  • Evaluation
    • Fine needle aspiration of the mass
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