Snapshot A 20-year-old man presents with a two-year history of motor restlessness that has progressed to uncontrollable choreiform movements. He has moderate dementia with a severe gait disturbance as well as agitation and problems with his mood. CT scan of the brain shows atrophy of the cerebral cortex and caudate nucleus. Introduction An autosomal dominant disorder characterized by login to view 3 more bullets Epidemiology login to view 5 more bullets Genetic login to view 8 more bullets Pathophysiology login to view 4 more bullets Presentation Symptoms login to view 5 more bullets Evaluation MRI login to view 1 more bullet Treatment Pharmacologic login to view 14 more bullets Prognosis, Prevention, and Complications Death inevitable Suicide common cause of death