Snapshot A 58-year-old man is brought by his wife due to worsening weakness and fatigue. She describes his movements as "sluggish." The patient reports difficulting with typing on his keyboard and buttoning up his pants. On physical exam, there is a "pill-rolling" tremor at rest that improves with purposeful movement. There is also increased resistance to passive movement at the wrist and elbow. He is started on levodopa and carbidopa. Introduction ↑ L-DOPA login to view 16 more bullets Dopamine receptor agonists login to view 2 more bullets ↑ Dopamine availability login to view 8 more bullets Preventing dopamine metabolism login to view 10 more bullets Anticholinergics login to view 6 more bullets