Snapshot A 46-year-old man presents to the emergency department due to severe pain of the first metatarsophalangeal (MTP) joint of acute onset. He describes the pain as 10/10 and sharp. Medical history is significant for obesity and hypertension and was recently started on furosemide. Social history is notable for alcohol use disorder managed with naltrexone. He reports to recently increasing his alcohol intake due to environmental stresses. On physical exam, the right first MTP joint appears erythematous, swollen, and is warm. Preparations are made to perform an arthrocentesis. Introduction Clinical definition login to view 1 more bullet Epidemiology login to view 4 more bullets Etiology login to view 18 more bullets Pathogenesis login to view 8 more bullets Prognosis login to view 3 more bullets Presentation Symptoms login to view 5 more bullets Physical exam login to view 13 more bullets Studies Labs login to view 3 more bullets Synovial fluid analysis login to view 3 more bullets Making the diagnosis login to view 2 more bullets Differential Septic arthritis login to view 6 more bullets Pseudogout login to view 4 more bullets Treatment Management approach login to view 4 more bullets Conservative login to view 7 more bullets Medical login to view 19 more bullets